The Uruguay River is a major river in South America. Its headwaters originate in Brazil's coastal range. The river forms parts of the boundaries of Brazil, Uruguay and Argentina before eventually joining the Río de la Plata.
The Yabotí Biosphere Reserve is located in the Misiones province of northeastern Argentina. The reserve is part of the Misiones Rainforest Corridor, within the Amazon Rainforest region, which is home to some of the most traditional villages of the Guaraní peoples.